“Do not call them bastards”: Shakespeare as an invasive species

Undocumented embryos: do not trash them, FISH them.

Pronuclei formation is routinely assessed 16-20 h after oocyte insemination in in-vitro fertilization (IVF). Occasionally, the pronuclei disappear before this time, rendering them as 'undocumented'. Since the number of pronuclei detected is used to distinguish normal from abnormal embryos in the context of ploidy, the diploidy of undocumented embryos is questionable, and therefore they are rout...

Molecular approaches to diagnosis of invasive aspergillosis what we know and what we do not know.

Invasive aspergillosis (IA) are a major complication in immunocompromized patients where can be serious and rapidly fatal. Early diagnosis and early appropriate antifungal treatment is important in reducing mortality and morbidity. But despite many efforts to develop detection methods, the diagnosis of IA still remains challenging and current conventional methods are limited for adequate diagno...

Databases, But Not As We Know Them

What shall we call them?

When last discussed in Pediatrics in 2002, the American Academy of Pediatrics (AAP) Committee on Psychosocial Aspects of Child and Family Health statement “Coparent or Second-Parent Adoption by Same-Sex Parents”2 (reaffirmed February 2010) and the accompanying technical report written by Ellen Perrin, MD, FAAP,3 drew much attention and engendered controversy both within the AAP and outside of i...

Research antibodies: do not use them to stain your reputation.

IN A RECENT ROUNDTABLE organized by the Federation of American Societies For Experimental Biology (FASEB) on data reproducibility and antibodies (8), we learned how the sale and use of antibodies place both basic and preclinical research at risk of losing support from the public at large, from funding agencies, and from Congress. Hundreds of millions of dollars are wasted annually on poor data ...